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American Science Cloud Documentation

Welcome to the official documentation for the American Science Cloud (AmSC), a national-scale scientific computing platform that connects researchers to high-performance computing resources, AI/ML services, and scientific data infrastructure across the U.S. Department of Energy (DOE) national laboratory ecosystem.

AmSC provides a unified environment for scientific workflows, enabling researchers to access, move, and analyze data, run large-scale computations, and leverage cutting-edge AI and machine learning capabilities, all through a common set of interfaces and services.

AmSC Technical Documentation​

This site serves as the operational portal for AmSC users. From here you can:

  • View instructions to
  • View training materials
  • Request support for AmSC services
  • Learn about AmSC capabilities and workflows

New to Genesis?​

Genesis Education and Resources (GEAR)​

If you are participating in the Genesis Mission through a DOE Request for Applications (RFA), you may also wish to visit the GEAR (Genesis Education and Resources) website, gear.doe.gov, for additional onboarding guidance. GEAR provides an overview of the Genesis ecosystem, including information on:

  • Data Management
  • Safety & Security
  • AI & Agents
  • Resource Requests
  • Genesis program guidance

Genesis Mission RFA repository​

The RFA repository collects practical guidance, reference cards, templates, and training materials to help Genesis Mission RFA teams adopt AI, agents, and sound data practices in their scientific workflows. The materials are organized into four areas: AI and agents, data management, AI safety and security, and general resources.